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EHSRC Pilot Grant Program - Funded Applications

2001 - 2005

 

  2001      

Investigator(s):   
Pedro Alvarez, Professor, Civil and Environmental Engineering; Donguk Kim, Assistant Professor, Inje University, Kimhae, Kyongnam, South Korea
Project Title:    
Enhanced Anaerobic Bioremediation of Gasohol Spills
Year Funded: 
 2001
Amount Received: 
$20,000
Publications:
  1. Ruiz-Aguilar, GM, Fernandez-Sanchez, JM, Kane, SR, Kim, D, Alvarez, PJJ. Effect of ethanol and methyl-tert-butyl ether on momaromatic hydrocarbon biodegradation: response variability for different aquifer materials under various electron-accepting conditions.  Environ Toxicol Chem. 21(12):2631-9, 2002.
Grant Awards:
  1. National Science Foundation.  P. Alvarez, PI.  Environmental Impacts of Ethanol in Gasoline: A Planning Trip to Brazil.  8/15/01 – 8/14/02.  $12,915.
  2. American Petroleum Institute.  P. Alvarez, PI.  Effect of Ethanol on BTEX Plume Length.  8/1/01 – 7/31/02.  $38,994.
  3. National Science Foundation 0412046.  P. Alvarez, PI.  International Workshop: U.S.-Latin American Caribbean Environmental Problems and Sustainable Solutions, Cartagena, Colombia, May 2004.  OISE INTERNATIONAL PLAN & WORKSHOPS, ENVIRONMENTAL ENGINEERING.  $28,464 04/15/2004
  4. National Science Foundation 0410145.  P. Alvarez, PI.   U.S.-Brazil Planning Visit: Environmental Impacts of Ethanol in Gasoline.  OISE Americas Program 02/01/2004.  $3,003.
  5. National Science Foundation  0224561.  P. Alvarez, PI.  SGER: Remediation of PAHs in the Rhizosphere of Tropical Plants. 09/01/2000.  $100,000.

Investigator(s):   
Leslie Dennis, Assistant Professor, Epidemiology; Laura Beane-Freeman, PhD Candidate; Epidemiology; Peter S. Thorne, Professor, Occupational and Environmental Health
Project Title:    
Arsenic Exposure and Melanoma in Iowa
Year Funded: 
2001
Amount Received: 
$20,000
Publications
  1. Arsenic Exposure and Melanoma in Iowa. Laura Beane-Freeman PhD Thesis, March 2003.
  2. Beane Freeman LE, Dennis LK, Lynch, CF, Thorne PS, Just CL.  Toenail arsenic content and cutaneous melanoma in Iowa.  Am. J. Epidemiol., 160(7):679-687, 2004.
Grant Awards:
  1. Innovations/Enhancements for a Consortium of Big-10 University Research & Training Reactors' Mini-Grant Program: PI, Cancer in Iowa as Related to Levels of Trace Elements in Toenails, Soil and Food, $9,923, from Jul 14, 2003 to May 31, 2004.
  2. NIH/NCI:PI, Trace Elements among Iowa Pesticide Applicators, $100,000, from Jul 1, 2003 to Jun 30, 2005.
  3. National Institutes of Health: Mentor, Meta-Analysis of Melanoma and Nevi, Marta Van Beek, PI, $87,826, from Jul 1, 2001 to Jun 30, 2003.
  4. American Cancer Society (ACS):PI, Cumulative Sun Exposure and Melanoma: A Meta-Analysis, $261,000, from Jan 1, 2004 to Dec 31, 2005.

Investigator(s):   
Caroline George, Assistant Professor, Pediatrics; Peter S. Thorne, Professor, Occupational and Environmental Health
Project Title:    
Subchronic Endotoxin Lung Injury as a Model to Study Airway Wall Remodeling
Year Funded: 
2001
Amount Received: 
$20,000
Publications:
George CL, White ML, O'Neill ME, Thorne PS, Schwartz DA, Snyder JM.  Altered surfactant protein A gene expression and protein metabolism associated with repeat exposure to inhaled endotoxin.  Am J Physiol Lung Cell Mol Physiol. 285(6):L1337-44, 2003.

Investigator(s):   
Stephen J. Reynolds, Professor, Occupational and Environmental Health; John C. Johnson, Director, Hazardous Waste Site Health Assessment Program, Iowa Department of Public Health; Peter S. Thorne, Professor, Occupational and Environmental Health
Project Title:    
 Worker Exposure to Airborne Bacteria and Endotoxic at Wastewater Treatment Plants
Year Funded: 
2001
Amount Received: 
$20,000

 

2002

Investigator(s):   
Michael Wichman, Chemist, University Hygienic Lab; John D. Vargo, Chemist, University Hygienic Lab; Dana W. Kolpin, Research Hydrologist, U.S. Geological Survey; Michael T. Meyer, Research Chemist, U.S. Geological Survey
Project Title:    
Method Development and Exploratory Monitoring for Human and Veterinary Pharmaceuticals in Surface, Waste, and Drinking Water
Year Funded: 
2001
Amount Received: 
$20,000
Publications:
  1. Kolpin DW, Skopec M, Meyer MT, Furlong ET, Zaugg SD.  Urban contribution of pharmaceuticals and other organic wastewater contaminants to streams during differing flow conditions.  Sci Total Environ. 2004 Jul 26;328(1-3):119-30.
  2. Stackelberg PE, Furlong ET, Meyer MT, Zaugg SD, Henderson AK, Reissman DB.  Persistence of pharmaceutical compounds and other organic wastewater contaminants in a conventional drinking-water-treatment plant.  Sci Total Environ. 2004 Aug 15;329(1-3):99-113.
  3. Boxall AB, Kolpin DW, Halling-Sorensen B, Tolls J.  Are veterinary medicines causing environmental risks?  Environ Sci Technol. 37(15):286A-294A, 2003. Review.
  4. Campagnolo ER, Johnson KR, Karpati A, Rubin CS, Kolpin DW, Meyer MT, Esteban JE, Currier RW, Smith K, Thu KM, McGeehin M.  Antimicrobial residues in animal waste and water resources proximal to large-scale swine and poultry feeding operations.  Sci Total Environ. 299(1-3):89-95, 2002.
  5. Kolpin DW, Furlong ET, Meyer MT, Thurman EM, Zaugg SD, Barber LB, Buxton HT.  Pharmaceuticals, hormones, and other organic wastewater contaminants in U.S. streams, 1999-2000: a national reconnaissance.  Environ Sci Technol. 36(6):1202-11, 2002.

Investigator(s):   
 Bryan Boulanger, Ph.D. Candidate, Civil and Environmental Engineering; Jerald L. Schnoor, Professor, Civil and Environmental Engineering; Keri C. Hornbuckle, Associate Professor, Civil and Environmental Engineering
Project Title:    
 Environmental Exposure Assessment of Perfluorooctane Sulfonate in Various Environmental Matrices
Year Funded: 
 2002
Amount Received: 
$20,000
Publications:
  1. Boulanger B, Peck AM, Schnoor JL, Hornbuckle KC.   Mass budget of perfluorooctane surfactants in Lake Ontario.  Environ Sci Technol. 2005 Jan 1;39(1):74-9. Erratum in: Environ Sci Technol. 2005 Mar 15;39(6):1920.
  2. Boulanger B, Vargo J, Schnoor JL, Hornbuckle KC.    Detection of perfluorooctane surfactants in Great Lakes water.  Environ Sci Technol. 2004 Aug 1;38(15):4064-70.

Investigator(s):   
Caroline George, Assistant Professor, Pediatrics; Katarina Kulhankova, Ph.D. Candidate, Occupational and Environmental Health; Peter S. Thorne, Professor, Occupational and Environmental Health
Project Title:    
Effects of Early Life Endotoxin Inhalation on Murine Hyperresponsiveness in Adulthood
Year Funded: 
2002
Amount Received: 
$20,000

Investigator(s):   
Peter S. Thorne, Professor, Occupation and Environmental Health; Brad Lester, PhD Candidate, Occupational and Environmental Health; Aaron Peck, PhD Candidate, Civil and Environmental Engineering; Keri Hornbuckle, Associate Professor, Civil and Environmental Engineering; Kelley J. Donham, Professor, Occupational and Environmental Health; Patrick O’Shaughnessy, Assistant Professor, Occupational and Environmental Health; David Osterberg, Associate Professor, Occupational and Environmental Health
Project Title:    
Ambient Air Quality in the Vicinity of Concentrated Animal Feeding Operations
Year Funded: 
2002
Amount Received: 
$20,000

Investigator(s):   
Leslie Dennis, Assistant Professor, Epidemiology; Linda Snetselaar, Associate Professor, Epidemiology; Peter S. Thorne, Professor, Occupational and Environmental Health
Project Title:    
Understanding Selenium Levels in Iowa and Their Association with Prostate Cancer
Year Funded: 
2002
Amount Received: 
$20,000
Grant Awards:
  1. NIH/NCI: L. Dennis, PI. Trace Elements among Iowa Pesticide Applicators, $100,000. 7/1/2003 – 6/30/2005

Investigator(s):   
Catherine Woodman, Associate Professor, Psychiatry; Greg Couser, Resident, Occupational and Environmental Health; Donald Black, Professor, Psychiatry
Project Title:    
Association Between Multiple Chemical Sensitivity and Anxiety Disorders
Year Funded: 
2002
Amount Received: 
$20,000
Publications:
  1. Woodman CL, Geist LJ, Vance S, Laxson C, Jones K, Kline JN.  Psychiatric disorders and survival after lung transplantation.  Psychosomatics. 1999 Jul-Aug;40(4):293-7

Investigator(s):   
Sigurdur Sigurdarson, Fellow Associate, Internal Medicine; Joel Kline, Associate Professor, Internal Medicine; Patrick O’Shaughnessy, Assistant Professor, Occupational and Environmental Health
Project Title:    
Exposure to Grain Dust and Ammonia in Asthmatic Subjects: A CAFO Model
Year Funded: 
2002
Amount Received: 
$20,000
Publications:
  1. Sigurdarson ST, O’Shaughnessy PT, Watt JA, Kline JN.  Experimental Human Exposure to Inhaled Grain Dust and Ammonia:  Towards A Model of Concentrated Animal Feeding Operations.  Am J Ind Med. 2004 Oct;46(4):345-8.

 

2003

Investigator(s):   
Richard Valentine, Professor, Civil and Environmental Engineering
Project Title:    
Influence of Riverbank Filtration on NDMA Formation Potential
Year Funded: 
2003
Amount Received: 
$20,000

Investigator(s):   
Patrick O’Shaughnessy, Professor, Occupational and Environmental
Health, Keri Hornbuckle, Associate Professor, Civil & Environmental Engineering
Project Title:    
Air Dispersion Modeling of Confined Animal Feeding Operations
Year Funded: 
2003
Amount Received: 
$18,800
Publications:
  1. Sigurdarson ST, O'Shaughnessy PT, Watt JA, Kline JN.   Experimental human exposure to inhaled grain dust and ammonia: towards a model of concentrated animal feeding operations.  Am J Ind Med. 2004 Oct;46(4):345-8.


Investigator(s):   
Hans-Joachim Lehmler, Associate Research Scientist, Occupational and Environmental Health; Keri Hornbuckle, Associate Professor, Civil & Environmental Engineering
Project Title:    
Enantoselective Enrichment of Chiral Polychlorinated Biphenyl (PCBs) Congeners in Complex Mixture in Vivo
Year Funded: 
2003
Amount Received: 
$20,000
Publications:
  1. Lehmler HJ, Robertson LW, Garrison AW, Kodavanti PR.  Effects of PCB 84 enantiomers on [3H]-phorbol ester binding in rat cerebellar granule cells and 45Ca2+-uptake in rat cerebellum.  Toxicol Lett. 2005 Apr 28;156(3):391-400. Epub 2005 Jan 23.
  2. I. Kania-Korwel, K.C. Hornbuckle, A. Peck, W.W. Sułkowski, G. Ludewig, L.W. Robertson, H.-J. Lehmler, Comparison of PCB congener profiles in tissues of PCB-treated rats. Organohalogen Compounds 2004, 66: 2874-2881.
  3. Kania-Korwel, G. Ludewig, L.W. Robertson, K.C. Hornbuckle, A. Peck, P. Espandiari, C.G. Gairola, W.W. Sułkowski, H.-J. Lehmler, Biochemical effects of an environmental Chlorofen mixture in comparison with Aroclor 1254 in rats.  Organohalogen Compounds 2004, 66: 2943-2950.
  4. H.-J. Lehmler, I. Kania-Korwel, J.K. Avants, K.C. Hornbuckle, W.W. Sulkowski, L.W. Robertson, W.A. Garrison, Distribution of chiral PCBs in selected tissues in the laboratory rat.  Organohalogen Compounds 2004, 66: 441-448.
  5. Kania-Korwel, K.C. Hornbuckle, A. Peck, G. Ludewig, L.W. Robertson, W.W. Sulkowski, P. Espandiari, C.G. Gairola, H.-J. Lehmler. Congener specific tissue distribution of Aroclor 1254 and a highly chlorinated environmental PCB mixture in rats.  Environ. Sci. Technol. 2005: 39, 3513-3520.
Grant Awards:
  1. NIH 1K25ES012475-01A1.  H-J Lehmler, PI.  Distribution of PCB Atropisomers.  9/3/04 – 7/31/09.  $662,948.

Investigator(s):   
Gabriele Ludewig, Occupational and Environmental Health; Larry W.
Robertson, Professor, Occupational and Environmental Health; Elaine Smith, Professor, Department of Epidemiology
Project Title:    
  Exploring the Mechanism(s) of Increased Prostate Cancer Risk after Exposure to Polychlorinated Biphenyls (PCBs)
Year Funded: 
2003
Amount Received: 
$20,000
Publications:
  1. Ritchie JM, Vial SL, Fuortes LJ, Robertson LW, Guo H, Reedy VE, Smith EM.  Comparison of proposed frameworks for grouping polychlorinated biphenyl congener data applied to a case-control pilot study of prostate cancer.  Environ Res. 2005 May;98(1):104-13.

Investigator(s):   
Sigurdur Sigurdarson, Fellow Associate, Occupational and Environmental Health; Gunnar Gundmundsson, Staff Physician, Department of Internal Medicine, University Hospital of Iceland, Joel N. Kline, Associate Professor, Department of Internal Medicine, Peter S. Thorne, Professor, Department of Occupational and Environmental Health; Kristin Thomasson, Chief Medical Officer, Administration of Occupational Safety and Health in Iceland.
Project Title:    
Respiratory Disease and the Agricultural Environment: A Study on Environmental Factors Associated with Respiratory Symptoms in Icelandic Farmers
Year Funded: 
2003
Amount Received: 
$20,000

 

2004

Investigator(s):   
Richard J. Milchak, Department of Internal Medicine; Joel N. Kline, Associate Professor, Department of Internal Medicine; Geoffrey McLennan, Professor, Department of Internal Medicine; Eric A. Hoffman, Professor, Department of Radiology
Project Title:    
High Resolution CT-Based Evaluation of Airway Responses to Endotoxin Inhalation
Year Funded: 
2004
Amount Received: 
$20,000

Investigator(s):   
Katarina Kulhankova, Department of Occupational and Environmental Health; Peter S. Thorne, Professor, Department of Occupational and Environmental Health; Caroline S. George, Assistant Professor, Department of Pediatrics; Geoffrey McLennan, Professor, Department of Internal Medicine; Joel N. Kline, Associate Professor, Department of Internal Medicine
Project Title:    
The Role of Neonatal and Juvenile Inhalation Exposures on Pulmonary Hyperresponsiveness and Lung Growth
Year Funded: 
2004
Amount Received: 
$20,000

Investigator(s):   
Caroline George, Department of Pediatrics; Jeanne Snyder, Professor, Department of Anatomy and Cell biology; Joel Kline, Associate Professor, Department of Internal Medicine; Patrick O’Shaughnessy, Associate Professor, Occupational and Environmental Health; Peter S. Thorne, Professor, Occupational and Environmental Health; Frank McCormack, Associate Professor, Department of Internal Medicine, University of Cincinnati
Project Title:    
The role of surfactant protein-A during early life environmental exposures
Year Funded: 
2004
Amount Received: 
$20,000

Investigator(s):   
Prabhat C. Goswami, Assistant Professor, Department of Radiation Oncology
Project Title:    
Polychlorinated Biphenyls, Intracellular Antioxidants and Cellular Proliferation
Year Funded: 
2004
Amount Received: 
$20,000

 

2005

Investigator(s):   
Kevin Doerschug, Assistant Professor, Department of Internal Medicine
Project Title:    
Oxidative stress and injury in exertion-associated environmental exposure
Year Funded: 
2005
Amount Received: 
$20,000

Investigator(s):   
Jonathan A. Doorn, Assistant Professor, College of Pharmacy
Project Title:    
Reactivity of Protein Nucleophiles toward an Aldehyde Intermediate of Dopamine Metabolism
Year Funded: 
2005
Amount Received: 
$20,000

Investigator(s):   
Suzana Hađina, Department of Occupational and Environmental Health; Peter S. Thorne, Professor, Department of Occupational and Environmental Health; Paul B. McCray, Professor, Department of Pediatrics; Jerrold P. Weiss, Professor, Department of Internal Medicine; Katarina Kulhankova, Graduate Research Assistant, Department of Occupational and Environmental Health
Project Title:    
The Role of MD-2 in Endotoxin Responsiveness in vivo
Year Funded: 
2005
Amount Received: 
$20,000

  Environmental Health Sciences Research Center, The University of Iowa, 100 Oakdale Campus, #178 IREH, Iowa City, IA 52242

Tel: (319) 335-4756 / Fax: (319) 335-4225 / E-mail: nancy-newkirk@uiowa.edu