Environmental Health Sciences Research Center

EHSRC Investigator Detail

COEC

Geoffrey McLennan, M.B.,B.S., F.R.A.C.P., Ph.D.
Professor of Internal Medicine - Pulmonary
Email: geoffrey-mclennan@uiowa.edu
Phone: (319) 353-8201
EHSRC Role(s):	Co-Director, Integrative Health Sciences Facility
	Member, Environmental Lung Disease Research Cluster

Dr. McLennan's clinical interests are in general pulmonology with a particular focus on diagnostic and therapeutic uses of bronchoscopy. His clinical research includes studies of new applications for fiber optic bronchoscopy.

Previous research relates to elastin metabolism in the lung and heparin as an antielastase on substance P in relation to human asthma, and in human alveolar macrophage function in lung cancer. Current research is in the development of and utility of advanced image analysis techniques in the lung. He is also actively involved in developing newer bronchoscopic techniques, especially virtual bronchoscopy, bronchoscopic fluorescence detection, bronchoscopic ultrasound, balloon bronchoplasty and bronchial stent placement, as well as in medical laser application. He has also undertaken clinical research in asthma, lung cancer, and pneumonia and continues to examine aspects of lung cancer in NCI funded studies.

Recent Publications

Lin CL, Tawhai MH, McLennan G, Hoffman EA. Characteristics of the turbulent laryngeal jet and its effect on airflow in the human intra-thoracic airways. Respir Physiol Neurobiol. 2007 Aug 1;157(2-3):295-309. Epub 2007 Feb 14.
2: Namati E, Chon D, Thiesse J, Hoffman EA, de Ryk J, Ross A, McLennan G. In vivo micro-CT lung imaging via a computer-controlled intermittent iso-pressure breath hold (IIBH) technique. Phys Med Biol. 2006 Dec 7;51(23):6061-75. Epub 2006 Nov 2.
3: Meyer CR, Johnson TD, McLennan G, Aberle DR, Kazerooni EA, Macmahon H, Mullan BF, Yankelevitz DF, van Beek EJ, Armato SG 3rd, McNitt-Gray MF, Reeves AP, Gur D, Henschke CI, Hoffman EA, Bland PH, Laderach G, Pais R, Qing D, Piker C, Guo J, Starkey A, Max D, Croft BY, Clarke LP. Evaluation of lung MDCT nodule annotation across radiologists and methods. Acad Radiol. 2006 Oct;13(10):1254-65.
4: Ferguson JS, Rippentrop JM, Fallon B, Ross AF, McLennan G. Management of obstructing pulmonary broncholithiasis with three-dimensional imaging and holmium laser lithotripsy. Chest. 2006 Sep;130(3):909-12.
5: Xu Y, van Beek EJ, Hwanjo Y, Guo J, McLennan G, Hoffman EA. Computer-aided classification of interstitial lung diseases via MDCT: 3D adaptive multiple feature method (3D AMFM). Acad Radiol. 2006 Aug;13(8):969-78.
6: Hoffman EA, Simon BA, McLennan G. State of the Art. A structural and functional assessment of the lung via multidetector-row computed tomography: phenotyping chronic obstructive pulmonary disease. Proc Am Thorac Soc. 2006 Aug;3(6):519-32. Review.
7: Xu Y, Sonka M, McLennan G, Guo J, Hoffman EA. MDCT-based 3-D texture classification of emphysema and early smoking related lung pathologies. IEEE Trans Med Imaging. 2006 Apr;25(4):464-75.