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Dr. Lehmler's main research interests are in the disposition and metabolism of chiral environmental contaminants, toxicity of perfluorinated surfactants, interaction of fluorinated materials with biological lipid assemblies, synthesis of halogenated POPs and their metabolites.
Recent Publications
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Xie W, Kania-Korwel I, Bummer PM, Lehmler HJ. Effect of potassium perfluorooctanesulfonate, perfluorooctanoate and octanesulfonate on the phase transition of dipalmitoylphosphatidylcholine (DPPC) bilayers. Biochim Biophys Acta. 2007 May;1768(5):1299-308. Epub 2007 Feb 9.
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Sadeghi-Aliabadi H, Chan K, Lehmler HJ, Robertson LW, O'Brien PJ. Molecular cytotoxic mechanisms of catecholic polychlorinated biphenyl metabolites in isolated rat hepatocytes. Chem Biol Interact. 2007 May 1;167(3):184-92. Epub 2007 Feb 23.
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Lehmler HJ. Perfluorocarbon compounds as vehicles for pulmonary drug delivery. Expert Opin Drug Deliv. 2007 May;4(3):247-62.
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Vyas SM, Kania-Korwel I, Lehmler HJ. Differences in the isomer composition of perfluoroctanesulfonyl (PFOS) derivatives. J Environ Sci Health A Tox Hazard Subst Environ Eng. 2007 Feb 15;42(3):249-55.
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Ghosh K, Vyas SM, Lehmler HJ, Rankin SE, Knutson BL. Tailoring porous silica films through supercritical carbon dioxide processing of fluorinated surfactant templates. J Phys Chem B. 2007 Jan 18;111(2):363-70.
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Kania-Korwel I, Shaikh NS, Hornbuckle KC, Robertson LW, Lehmler HJ. Enantioselective disposition of PCB 136 (2,2',3,3',6,6'-hexachlorobiphenyl) in C57BL/6 mice after oral and intraperitoneal administration. Chirality. 2007 Jan;19(1):56-66.
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H.-J. Lehmler, Rama Rao V.V.V.N.S., D. Nauduri, J.D. Vargo, S. Parkin, Synthesis and structure of environmentally relevant perfluorinated sulfonamides. J. Fluorine Chem. 2007: 128, 595-607.
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